Terminology Service for NFDI4Health

glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex

Go to external page http://purl.obolibrary.org/obo/GO_0000506


An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast. [ http://www.ncbi.nlm.nih.gov/pubmed/10944123 http://www.ncbi.nlm.nih.gov/pubmed/15163411 ]

Term info

Label

glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex

Synonyms
  • GPI-GlcNAc transferase complex
  • GPI-GnT complex
  • GPI-N-acetylglucosaminyltransferase complex
comment

Note that this term should not be confused with 'GPI-anchor transamidase complex ; GO:0042765', which represents a distinct complex with a different catalytic activity.

has obo namespace

cellular_component

id

GO:0000506