Terminology Service for NFDI4Health
DNA-binding transcription repressor activity, RNA polymerase II-specific
Go to external page
http://purl.obolibrary.org/obo/GO_0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units. [ ]
Term info
Label
DNA-binding transcription repressor activity, RNA polymerase II-specific
Synonyms
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
- transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
comment
Changed term label and definition https://github.com/geneontology/go-ontology/issues/16131 and https://github.com/geneontology/go-ontology/issues/16152 Merge terms see https://github.com/geneontology/go-ontology/issues/16534
created by
kchris
creation date
2010-10-26T03:56:48Z
has alternative id
GO:0001078, GO:0001210, GO:0001206, GO:0001214
has narrow synonym
transcriptional repressor activity, metal ion regulated sequence-specific DNA binding, metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription, proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific, RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription, metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding, distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding, transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding, RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding
has obo namespace
molecular_function
id
GO:0001227