Terminology Service for NFDI4Health
polkadots
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http://purl.obolibrary.org/obo/GO_0002096
A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals. [ http://www.ncbi.nlm.nih.gov/pubmed/14724296 http://www.ncbi.nlm.nih.gov/pubmed/16495340 ]
Term info
Label
polkadots
comment
Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots.
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cellular_component
id
GO:0002096