Terminology Service for NFDI4Health
membrane attack complex
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http://purl.obolibrary.org/obo/GO_0005579
A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. [ https://www.worldcat.org/search?q=bn%3A068340007X https://www.worldcat.org/search?q=bn%3A0198547684 https://www.worldcat.org/search?q=bn%3A0781735149 ]
Term info
Label
membrane attack complex
Synonyms
- MAC
- TCC
- terminal complement complex
has narrow synonym
membrane attack complex protein beta2 chain, membrane attack complex protein alphaM chain
has obo namespace
cellular_component
id
GO:0005579