nuclear pre-replicative complex
A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins. [ http://www.ncbi.nlm.nih.gov/pubmed/15222894 ]
Term info
nuclear pre-replicative complex
- eukaryotic pre-replicative complex
pre-replicative complex
cellular_component
pre-RC
GO:0005656
Term relations
- pre-replicative complex
- part of some nucleoplasm
- has part some MCM complex
- has part some origin recognition complex