Terminology Service for NFDI4Health
nuclear cap binding complex
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http://purl.obolibrary.org/obo/GO_0005846
A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export. [ http://www.ncbi.nlm.nih.gov/pubmed/16043498 ]
Term info
Label
nuclear cap binding complex
comment
Note that this complex can be found in the cytoplasm as well as the nucleus.
has narrow synonym
snRNA cap binding complex, mRNA cap binding complex, NCBP-NIP1 complex
has obo namespace
cellular_component
id
GO:0005846