Terminology Service for NFDI4Health
glycerophosphate shuttle
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http://purl.obolibrary.org/obo/GO_0006127
The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle. [ http://www.ncbi.nlm.nih.gov/pubmed/16368075 https://www.worldcat.org/search?q=bn%3A0716720094 ]
Term info
Term relations
Subclass of:
- organophosphate metabolic process
- primary alcohol metabolic process
- NADH oxidation
- phosphate-containing compound metabolic process
- carbohydrate derivative metabolic process
- cellular ketone metabolic process
- has part some sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity
- has part some glycerol-3-phosphate dehydrogenase [NAD+] activity
- part of some respiratory electron transport chain