Terminology Service for NFDI4Health

lagging strand elongation

Go to external page http://purl.obolibrary.org/obo/GO_0006273


The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork. [ https://www.worldcat.org/search?q=bn%3A071673706X https://www.worldcat.org/search?q=bn%3A0815316194 ]

Term info

Label

lagging strand elongation

comment

Changed definition https://github.com/geneontology/go-ontology/issues/12633

has obo namespace

biological_process

id

GO:0006273