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chromatin silencing

Go to external page http://purl.obolibrary.org/obo/GO_0006342

Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. [ http://www.ncbi.nlm.nih.gov/pubmed/10219245 ]

Term info

Label

chromatin silencing

Synonyms
  • TGS
  • chromatin-mediated maintenance of transcriptional inactivation
  • chromatin-mediated silencing
  • transcriptional gene silencing
comment

Note that this process is the opposite of chromatin-mediated maintenance of transcription. This regulation is exemplified by members of the Polycomb group, which maintain the inactive state of homeotic gene transcription.

has alternative id

GO:0016440

has obo namespace

biological_process

has related synonym

heterochromatic silencing

id

GO:0006342