Terminology Service for NFDI4Health

DNA-templated transcription, initiation

Go to external page http://purl.obolibrary.org/obo/GO_0006352


Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription. [ http://www.ncbi.nlm.nih.gov/pubmed/18280161 ]

Term info

Label

DNA-templated transcription, initiation

Synonyms
  • DNA-dependent RNA polymerase complex assembly at promoter
  • DNA-dependent transcription, initiation
  • initiation of DNA-dependent transcription
  • initiation of transcription, DNA-dependent
database cross reference
Subsets

goslim_yeast

comment

Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.

has obo namespace

biological_process

has related synonym

transcription initiation factor activity, transcription initiation, DNA-dependent

id

GO:0006352