Terminology Service for NFDI4Health

gene silencing

Go to external page http://purl.obolibrary.org/obo/GO_0016458


Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression. [ ]

Term info

Label

gene silencing

database cross reference
Subsets

goslim_drosophila, goslim_pir

comment

This is a rather broad grouping term. While it was originally defined for long-term, heritable, epigenetic effects, short term effects on expression mediated by RNA are also frequently referred to as gene silencing, and are grouped under this class.

has narrow synonym

long-term maintenance of gene inactivation

has obo namespace

biological_process

id

GO:0016458