retromer, tubulation complex
The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6. [ http://www.ncbi.nlm.nih.gov/pubmed/9700157 http://www.ncbi.nlm.nih.gov/pubmed/26220253 ]
Term info
retromer, tubulation complex
- SNX-BAR dimer
- heterodimeric membrane-deforming retromer subcomplex
- retromer complex, outer shell
cellular_component
GO:0030905