nuclear pore outer ring
A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates). [ http://www.ncbi.nlm.nih.gov/pubmed/18046406 http://www.ncbi.nlm.nih.gov/pubmed/20947011 http://www.ncbi.nlm.nih.gov/pubmed/22419078 http://www.ncbi.nlm.nih.gov/pubmed/19524430 ]
Term info
nuclear pore outer ring
- Nup107-120 complex
- Nup107-160 complex
- Nup84 complex
cellular_component
GO:0031080