Terminology Service for NFDI4Health
Elongator holoenzyme complex
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http://purl.obolibrary.org/obo/GO_0033588
A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes. [ http://www.ncbi.nlm.nih.gov/pubmed/11435442 http://www.ncbi.nlm.nih.gov/pubmed/18755837 http://www.ncbi.nlm.nih.gov/pubmed/17018299 http://www.ncbi.nlm.nih.gov/pubmed/11689709 http://www.ncbi.nlm.nih.gov/pubmed/15769872 http://www.ncbi.nlm.nih.gov/pubmed/23165209 ]
Term info
Label
Elongator holoenzyme complex
comment
Despite its name, this complex is no longer thought to be directly involved in transcriptional elongation (PMID:23165209).
has alternative id
GO:0033589
has obo namespace
cellular_component
has related synonym
Elongator core complex
id
GO:0033588