Terminology Service for NFDI4Health

Derlin-1 retrotranslocation complex

Go to external page http://purl.obolibrary.org/obo/GO_0036513


A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel. [ http://www.ncbi.nlm.nih.gov/pubmed/16186510 http://www.ncbi.nlm.nih.gov/pubmed/15215856 ]

Term info

Label

Derlin-1 retrotranslocation complex

Synonyms
  • Derlin-1 complex
  • Derlin-1 protein dislocation complex
  • Derlin-1 retro-translocation complex
  • Derlin-1 retrotranslocon
  • ERAD protein dislocation complex
comment

The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.

created by

rebeccafoulger

creation date

2015-07-01T10:17:30Z

has obo namespace

cellular_component

id

GO:0036513