Terminology Service for NFDI4Health
GPI-anchor transamidase complex
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http://purl.obolibrary.org/obo/GO_0042765
An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor. [ http://www.ncbi.nlm.nih.gov/pubmed/12802054 ]
Term info
Label
GPI-anchor transamidase complex
Synonyms
- GPIT complex
comment
Note that this term should not be confused with 'glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506', which represents a distinct complex with a different catalytic activity.
has obo namespace
cellular_component
id
GO:0042765