Terminology Service for NFDI4Health
post-translational protein modification
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http://purl.obolibrary.org/obo/GO_0043687
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. [ ]
Term info
Label
post-translational protein modification
Synonyms
- PTM
- post-translational amino acid modification
- post-translational modification
- posttranslational amino acid modification
- posttranslational modification
- posttranslational protein modification
comment
This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.
has obo namespace
biological_process
id
GO:0043687