Terminology Service for NFDI4Health
retroviral 3' processing activity
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http://purl.obolibrary.org/obo/GO_0044824
The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls. [ http://www.ncbi.nlm.nih.gov/pubmed/22580823 https://www.reactome.org/content/detail/R-HSA-164522 ]
Term info
Label
retroviral 3' processing activity
Synonyms
- 3' processing reaction
- 3'-processing activity
comment
This reaction may serve to remove heterogeneous extra bases from the viral DNA end, and to stabilize the integrase-DNA complex. The chemistry of cleavage is a simple hydrolysis by single-step transesterification.
created by
janelomax
creation date
2014-02-04T14:51:24Z
has obo namespace
molecular_function
id
GO:0044824