Terminology Service for NFDI4Health
cytosolic oxoglutarate dehydrogenase complex
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http://purl.obolibrary.org/obo/GO_0045248
A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2). [ http://www.ncbi.nlm.nih.gov/pubmed/10848975 ]
Term info
Label
cytosolic oxoglutarate dehydrogenase complex
comment
See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.
has obo namespace
cellular_component
id
GO:0045248