Terminology Service for NFDI4Health
pyruvate dehydrogenase complex
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http://purl.obolibrary.org/obo/GO_0045254
Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). [ https://www.worldcat.org/search?q=bn%3A0716720094 ]
Term info
Label
pyruvate dehydrogenase complex
Synonyms
- pyruvate dehydrogenase complex (lipoamide)
Subsets
goslim_pir
comment
Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.
has alternative id
GO:0009364
has broad synonym
dihydrolipoyl dehydrogenase complex
has obo namespace
cellular_component
id
GO:0045254