Terminology Service for NFDI4Health

lipopolysaccharide receptor complex

Go to external page http://purl.obolibrary.org/obo/GO_0046696


A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens. [ http://www.ncbi.nlm.nih.gov/pubmed/9665271 http://www.ncbi.nlm.nih.gov/pubmed/11706042 ]

Term info

Label

lipopolysaccharide receptor complex

Synonyms
  • LPS receptor complex
comment

Note that this term should not be used to refer to CD14 alone, but the multiprotein receptor complex that it is part of.

has obo namespace

cellular_component

id

GO:0046696