Terminology Service for NFDI4Health

Tapasin-ERp57 complex

Go to external page http://purl.obolibrary.org/obo/GO_0061779


Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role. [ http://www.ncbi.nlm.nih.gov/pubmed/17603487 ]

Term info

Label

Tapasin-ERp57 complex

creation date

2016-08-05T12:12:08Z

has obo namespace

cellular_component

id

GO:0061779