Terminology Service for NFDI4Health

R-loop disassembly

Go to external page http://purl.obolibrary.org/obo/GO_0062176


A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability. [ http://www.ncbi.nlm.nih.gov/pubmed/28790157 ]

Term info

Label

R-loop disassembly

creation date

2019-11-19T12:47:04Z

has obo namespace

biological_process

id

GO:0062176