R-loop disassembly
A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability. [ http://www.ncbi.nlm.nih.gov/pubmed/28790157 ]
Term info
R-loop disassembly
dph
2019-11-19T12:47:04Z
biological_process
GO:0062176