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negative regulation of release of cytochrome c from mitochondria

http://purl.obolibrary.org/obo/GO_0090201

Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. [ ]

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Label

negative regulation of release of cytochrome c from mitochondria

comment

The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and negatively regulate this process.

created by

tanyaberardini

creation date

2009-12-18T11:35:20Z

has obo namespace

biological_process

GO:0090201

Term relations

Equivalent to:

biological_process and negatively regulates some release of cytochrome c from mitochondria

Subclass of: