Terminology Service for NFDI4Health
JSON

apoptotic signaling pathway

Go to external page http://purl.obolibrary.org/obo/GO_0097190

A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. [ ]

Term info

Label

apoptotic signaling pathway

Synonyms
  • apoptotic signalling pathway
  • induction of apoptosis by extracellular signals
comment

This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.

created by

paola

creation date

2011-11-23T09:30:23Z

has alternative id

GO:0008624

has obo namespace

biological_process

id

GO:0097190