Terminology Service for NFDI4Health
mitochondrial outer membrane permeabilization
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http://purl.obolibrary.org/obo/GO_0097345
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway. [ http://www.ncbi.nlm.nih.gov/pubmed/21041309 ]
Term info
Label
mitochondrial outer membrane permeabilization
Synonyms
- MOMP
comment
BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively).
created by
paola
creation date
2012-06-19T04:06:54Z
has broad synonym
mitochondrial outer membrane permeabilization during apoptotic cell death, mitochondrial outer membrane permeabilization
has obo namespace
biological_process
id
GO:0097345