ventral disc
Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence. [ https://www.worldcat.org/search?q=bn%3A9780124260207 http://www.ncbi.nlm.nih.gov/pubmed/4777416 http://www.ncbi.nlm.nih.gov/pubmed/11432808 http://www.ncbi.nlm.nih.gov/pubmed/5961344 ]
Term info
ventral disc
- ventral adhesive disc
Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
paola
2014-04-03T11:29:58Z
cellular_component
adhesive disc, ventral disk
GO:0097597
Term relations
- organelle
- has part some ventral disc lateral crest
- has part some ventral disc dorsal microribbon
- has part some ventral disc crossbridge
- has part some ventral disc overlap zone