Terminology Service for NFDI4Health

primosome complex

Go to external page http://purl.obolibrary.org/obo/GO_1990077


Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart. [ http://www.ncbi.nlm.nih.gov/pubmed/21856207 ]

Term info

Label

primosome complex

Synonyms
  • primosome
creation date

2013-04-26T11:55:28Z

has obo namespace

cellular_component

id

GO:1990077

Term relations