Terminology Service for NFDI4Health

Bfa1-Bub2 complex

Go to external page http://purl.obolibrary.org/obo/GO_1990334


A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation. [ http://www.ncbi.nlm.nih.gov/pubmed/16449187 ]

Term info

Label

Bfa1-Bub2 complex

database cross reference
creation date

2014-03-17T14:34:21Z

has obo namespace

cellular_component

id

GO:1990334

Term relations