Bfa1-Bub2 complex
A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation. [ http://www.ncbi.nlm.nih.gov/pubmed/16449187 ]
Term info
Bfa1-Bub2 complex
bhm
2014-03-17T14:34:21Z
cellular_component
GO:1990334