Terminology Service for NFDI4Health

EFF-1 complex

Go to external page http://purl.obolibrary.org/obo/GO_1990392


A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer. [ http://www.ncbi.nlm.nih.gov/pubmed/24725407 ]

Term info

Label

EFF-1 complex

database cross reference
comment

An example of this is eff-1 in C. elegans (G5ECA1) in PMID:24725407 (inferred from direct assay).

creation date

2014-06-04T14:45:02Z

has obo namespace

cellular_component

id

GO:1990392