ESCRT IV complex
An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1. [ http://www.ncbi.nlm.nih.gov/pubmed/24456136 http://www.ncbi.nlm.nih.gov/pubmed/26775243 http://www.ncbi.nlm.nih.gov/pubmed/20696398 http://www.ncbi.nlm.nih.gov/pubmed/20653365 http://www.ncbi.nlm.nih.gov/pubmed/21925211 http://www.ncbi.nlm.nih.gov/pubmed/25164817 ]
Term info
ESCRT IV complex
- ESCRT-IV
pr
2015-01-29T10:02:30Z
Vps4-Vta1 complex, VPS4A-VPS4B, VPS4A/B complex
cellular_component
vacuolar protein sorting-associated complex, Vps4 complex, Vta1-Vps4 complex
GO:1990621