Terminology Service for NFDI4Health

ESCRT IV complex

Go to external page http://purl.obolibrary.org/obo/GO_1990621


An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1. [ http://www.ncbi.nlm.nih.gov/pubmed/24456136 http://www.ncbi.nlm.nih.gov/pubmed/26775243 http://www.ncbi.nlm.nih.gov/pubmed/20696398 http://www.ncbi.nlm.nih.gov/pubmed/20653365 http://www.ncbi.nlm.nih.gov/pubmed/21925211 http://www.ncbi.nlm.nih.gov/pubmed/25164817 ]

Term info

Label

ESCRT IV complex

Synonyms
  • ESCRT-IV
database cross reference
creation date

2015-01-29T10:02:30Z

has narrow synonym

Vps4-Vta1 complex, VPS4A-VPS4B, VPS4A/B complex

has obo namespace

cellular_component

has related synonym

vacuolar protein sorting-associated complex, Vps4 complex, Vta1-Vps4 complex

id

GO:1990621