Terminology Service for NFDI4Health
GLI-SUFU complex
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http://purl.obolibrary.org/obo/GO_1990788
A protein repressing GLI's transcription factor activity when SMO signalling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins. [ http://www.ncbi.nlm.nih.gov/pubmed/24311597 ]
Term info
Label
GLI-SUFU complex
comment
An example of this is SUFU in human (Q9UMX1) in PMID:24311597 (inferred from direct assay).
created by
bhm
creation date
2015-06-26T13:49:47Z
has obo namespace
cellular_component
id
GO:1990788