Terminology Service < Semantic Lookup Platform

All terms in GO

Label	Id	Description
chromatin reprogramming in the zygote	GO_0044725	[The global reprogramming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process.]
DNA methylation involved in embryo development	GO_0043045	[The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression.]
protection of DNA demethylation of female pronucleus	GO_0044726	[The protection of the maternal genome from DNA demethylation in the zygote following fertilization.]
regulation of DNA methylation	GO_0044030	[Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.]
DNA demethylation of male pronucleus	GO_0044727	[The active DNA demethylation of the paternal genome that takes place before the first cell division.]
DNA methylation or demethylation	GO_0044728	[The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule.]
DNA modification	GO_0006304	[The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.]
obsolete ubiquitin-like hydrolase activity	GO_0019790	[OBSOLETE. (Was not defined before being made obsolete).]
hemi-methylated DNA-binding	GO_0044729	[Interacting selectively and non-covalently with double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.]
double-stranded DNA binding	GO_0003690	[Interacting selectively and non-covalently with double-stranded DNA.]
FAT10 activating enzyme activity	GO_0019780	[Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.]
NEDD8 activating enzyme activity	GO_0019781	[Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.]
ISG15 activating enzyme activity	GO_0019782	[Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.]
ubiquitin-like protein-specific protease activity	GO_0019783	[Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated.]
cysteine-type peptidase activity	GO_0008234	[Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.]
NEDD8-specific protease activity	GO_0019784	[Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates.]
ISG15-specific protease activity	GO_0019785	[Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates.]
negative regulation of imaginal disc-derived wing size	GO_0044720	[Any process that reduces the size of an imaginal disc-derived wing.]
Atg8-specific protease activity	GO_0019786	[Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.]
catalytic activity, acting on a protein	GO_0140096	[Catalytic activity that acts to modify a protein.]