Terminology Service for NFDI4Health
5-aminolevulinic acid
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http://purl.obolibrary.org/obo/CHEBI_17549
The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Term info
Label
5-aminolevulinic acid
Synonyms
- 5-amino-4-oxopentanoic acid
Subsets
3_STAR
charge
0
formula
C5H9NO3
has alternative id
CHEBI:2034, CHEBI:20547
has obo namespace
chebi_ontology
has related synonym
delta-ALA, aminolevulinic acid, 5-Amino-4-oxovaleric acid, 5-Aminolevulinate, delta-aminolevulinic acid, dALA, 5-Amino-4-oxopentanoate, 5-ALA
id
CHEBI:17549
inchi
InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)
inchikey
ZGXJTSGNIOSYLO-UHFFFAOYSA-N
mass
131.12990
monoisotopicmass
131.05824
smiles
NCC(=O)CCC(O)=O
Term relations
Subclass of:
- delta-amino acid
- 4-oxo monocarboxylic acid
- is tautomer of some 5-ammoniolevulinate
- has role some mouse metabolite
- has functional parent some 4-oxopentanoic acid
- has role some antineoplastic agent
- has role some Saccharomyces cerevisiae metabolite
- has role some human metabolite
- has role some photosensitizing agent
- is conjugate acid of some 5-aminolevulinate
- has role some prodrug
- has role some Escherichia coli metabolite
- has role some dermatologic drug
- is conjugate base of some 5-ammoniolevulinic acid
- has role some plant metabolite