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cortisol

Go to external page http://purl.obolibrary.org/obo/CHEBI_17650

A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses

Term info

Label

cortisol

Synonyms
  • 11beta,17,21-trihydroxypregn-4-ene-3,20-dione
  • Cortisol
  • cortisol
database cross reference
Subsets

3_STAR

INN
hydrocortisone [ ChemIDplus ]

INN
hidrocortisona [ ChemIDplus ]

INN
hydrocortisonum [ ChemIDplus ]

IUPAC NAME
11beta,17,21-trihydroxypregn-4-ene-3,20-dione [ IUPAC ]

charge

0

formula

C21H30O5

has alternative id

CHEBI:14023, CHEBI:24633, CHEBI:58221, CHEBI:3893

has obo namespace

chebi_ontology

has related synonym

hidrocortisona, hydrocortisonum, Kendall's compound F, 4-pregnen-11beta,17alpha,21-triol-3,20-dione, hydrocortisone, 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione, 11beta-hydrocortisone, Hydrocortisone, Reichstein's substance M, 17-hydroxycorticosterone, (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione

id

CHEBI:17650

inchi

InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

inchikey

JYGXADMDTFJGBT-VWUMJDOOSA-N

mass

362.45990

monoisotopicmass

362.20932

smiles

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO