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3,3',5-triiodo-L-thyronine

Go to external page http://purl.obolibrary.org/obo/CHEBI_18258

An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Term info

Label

3,3',5-triiodo-L-thyronine

Synonyms
  • 3,3',5-triiodo-L-thyronine
database cross reference
Subsets

3_STAR

BRAND NAME
Tresitope [ DrugBank ]

INN
liothyronine [ ChemIDplus ]

BRAND NAME
Tertroxin [ DrugBank ]

IUPAC NAME
3,3',5-triiodo-L-thyronine [ IUPAC ]

INN
liotironina [ ChemIDplus ]

INN
liothyroninum [ ChemIDplus ]

INN
liothyronine [ ChEBI ]

charge

0

formula

C15H12I3NO4

has alternative id

CHEBI:9722, CHEBI:13059, CHEBI:45840, CHEBI:19894, CHEBI:11702, CHEBI:11701

has obo namespace

chebi_ontology

has related synonym

L-3,5,3'-Triiodothyronine, 3,5,3'-Triiodo-L-thyronine, 3,5,3'-Triiodothyronine, L-T3, liothyroninum, 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine, Tresitope, liotironina, Liothyronine, Tertroxin, Triiodothyronine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, liothyronine, T3, 3,5,3'TRIIODOTHYRONINE

id

CHEBI:18258

inchi

InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

inchikey

AUYYCJSJGJYCDS-LBPRGKRZSA-N

mass

650.97350

monoisotopicmass

650.79004

smiles

N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O