Terminology Service for NFDI4Health

proton-transporting two-sector ATPase complex

Go to external page http://purl.obolibrary.org/obo/GO_0016469


A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible. [ https://www.worldcat.org/search?q=bn%3A0716743663 http://www.ncbi.nlm.nih.gov/pubmed/16691483 ]

Term info

Label

proton-transporting two-sector ATPase complex

Synonyms
  • hydrogen-transporting two-sector ATPase complex
Subsets

goslim_metagenomics, goslim_pir

has obo namespace

cellular_component

has related synonym

vacuolar hydrogen-transporting ATPase

id

GO:0016469

Term relations