An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. [ http://www.ncbi.nlm.nih.gov/pubmed/20200518 http://www.ncbi.nlm.nih.gov/pubmed/18007680 http://www.ncbi.nlm.nih.gov/pubmed/18000958 https://www.worldcat.org/search?q=bn%3A0781735149 http://www.ncbi.nlm.nih.gov/pubmed/20065995 ]