execution phase of apoptosis
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. [ http://www.ncbi.nlm.nih.gov/pubmed/21760595 ]
Term info
execution phase of apoptosis
- execution phase of apoptotic process
paola
2011-11-23T09:45:24Z
apoptosis
biological_process
GO:0097194