Terminology Service for NFDI4Health

Microcephaly

Go to external page http://purl.obolibrary.org/obo/HP_0000252


Head circumference below 2 standard deviations below the mean for age and gender. [ http://www.ncbi.nlm.nih.gov/pubmed/9683597 http://www.ncbi.nlm.nih.gov/pubmed/19125436 http://www.ncbi.nlm.nih.gov/pubmed/25465325 ]

Term info

Label

Microcephaly

Synonyms
  • Abnormally small cranium
  • Abnormally small skull
  • Decreased circumference of cranium
  • Decreased size of cranium
  • Decreased size of skull
  • Reduced head circumference
  • Small head circumference
  • small calvarium
  • small cranium
database cross reference
Subsets

hposlim_core

layperson term
Small head circumference

layperson term
Small head [ ORCID : 0000-0001-5889-4463 ]

layperson term
Small skull [ ORCID : 0000-0001-5889-4463 ]

layperson term
Decreased size of skull [ ORCID : 0000-0001-5889-4463 ]

layperson term
Decreased size of head [ ORCID : 0000-0001-5889-4463 ]

layperson term
Abnormally small head [ ORCID : 0000-0001-5889-4463 ]

layperson term
Decreased circumference of cranium [ ORCID : 0000-0001-5889-4463 ]

layperson term
Reduced head circumference

layperson term
Abnormally small skull [ ORCID : 0000-0001-5889-4463 ]

comment

Head circumference is measured from just above the glabella (the most prominent point on the frontal bone above the root of the nose) to the most posterior prominent point of the occipital bone using a tape measure. Some standard charts are organized by centiles [Hall et al. [2007]], others by standard deviations [Farkas, [1981]]. It is important to add an indication of how far below the normal standard the head circumference is if an accurate assessment of this can be made. Microcephaly is an absolute term. The term relative microcephaly can be used when the head size centile is less than the centile for height, for example, head size at the 3rd centile with height at the 75% for age and sex. On prenatal ultrasound, microcephaly is diagnosed if the head circumference or the biparietal diameter is more than three standard deviations below the mean.

has alternative id

HP:0005489, HP:0005497, HP:0005485, HP:0001366

has broad synonym

Decreased size of head, Abnormally small head, Small head, Small skull

has obo namespace

human_phenotype

id

HP:0000252