Terminology Service for NFDI4Health
Megaloblastic anemia
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http://purl.obolibrary.org/obo/HP_0001889
Anemia characterized by the presence of erythroblasts that are larger than normal (megaloblasts). [ ]
Term info
Label
Megaloblastic anemia
comment
Megaloblastic anemia can result from folic acid deficiency or vitamin B12 deficiency. Folate deficiency leads to an impairment of DNA synthesis such that the cell cycle cannot progress from the G2 growth stage to the mitosis stage, in turn leading to continuing cell growth without division, which presents as macrocytosis.
has alternative id
HP:0004858
has obo namespace
human_phenotype
id
HP:0001889