Terminology Service for NFDI4Health
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Aganglionic megacolon

Go to external page http://purl.obolibrary.org/obo/HP_0002251

An abnormality resulting from a lack of intestinal ganglion cells (i.e., an aganglionic section of bowel) that results in bowel obstruction with enlargement of the colon. [ http://www.ncbi.nlm.nih.gov/pubmed/17965226 ]

Term info

Label

Aganglionic megacolon

Synonyms
  • Congenital megacolon
  • Enlarged colon lacking nerve cells
  • Hirschsprung megacolon
  • Megacolon
database cross reference
Subsets

hposlim_core

layperson term
Enlarged colon lacking nerve cells [ orcid.org/0000-0002-6548-5200 ]

comment

Aganglionic megacolon is characterized by congenital absence of intrinsic ganglion cells in the myenteric (Auerbach) and submucosal (Meissner) plexuses of the gastrointestinal tract.

has alternative id

HP:0002606, HP:0002030, HP:0004391, HP:0002029

has obo namespace

human_phenotype

has related synonym

Hirschsprung disease

id

HP:0002251

Term relations