Absence of bactericidal oxidative respiratory burst in phagocytes
An absence of the phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity. [ http://amigo.geneontology.org/amigo/term/GO:0045728 ]
Term info
Absence of bactericidal oxidative respiratory burst in phagocytes
human_phenotype
HP:0002723
Term relations
- has_part some (
lacking processual parts and
inheres in some respiratory burst after phagocytosis and
has modifier some abnormal)