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Arterial calcification

Go to external page http://purl.obolibrary.org/obo/HP_0003207

Pathological deposition of calcium salts in one or more arteries. [ http://www.ncbi.nlm.nih.gov/pubmed/18519861 ]

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Arterial calcification

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Most individuals aged over 60 years have progressively enlarging deposits of calcium mineral in their major arteries. This vascular calcification reduces aortic and arterial elastance, which impairs cardiovascular hemodynamics, resulting in substantial morbidity and mortality in the form of hypertension, aortic stenosis, cardiac hypertrophy, myocardial and lower-limb ischemia, congestive heart failure, and compromised structural integrity.The severity and extent of mineralization reflect atherosclerotic plaque burden and strongly and independently predict cardiovascular morbidity and mortality. (From PMID:18519861).

created by

peter

creation date

2008-03-26T04:05:00Z

has alternative id

HP:0012455

has obo namespace

human_phenotype

id

HP:0003207

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