Terminology Service for NFDI4Health
Reduced factor XII activity
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http://purl.obolibrary.org/obo/HP_0004841
Decreased activity of coagulation factor XII. Factor XII (fXII) is part of the intrinsic coagulation pathway and binds to exposed collagen at site of vessel wall injury, activated by high-MW kininogen and kallikrein, thereby initiating the coagulation cascade. [ ]
Term info
Label
Reduced factor XII activity
Synonyms
- Factor XII deficiency
- Hageman factor deficiency
has alternative id
HP:0005551, HP:0008286, HP:0005514
has obo namespace
human_phenotype
id
HP:0004841