Terminology Service for NFDI4Health
Reduced protein S activity
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http://purl.obolibrary.org/obo/HP_0004855
An abnormality of coagulation related to a decreased concentration of vitamin K-dependent protein S. Protein S is a cofactor of protein C. [ ]
Term info
Label
Reduced protein S activity
comment
Protein S functions as a cofactor to Protein C in the inactivation of Factors Va and VIIIa in the coagulation pathway. Therefore, a defect in protein S is associated with an increased risk of thrombosis.
has narrow synonym
Protein S deficiency
has obo namespace
human_phenotype
id
HP:0004855