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Abnormality of the intrinsic pathway

http://purl.obolibrary.org/obo/HP_0010989

An abnormality of the intrinsic pathway (also known as the contact activation pathway) of the coagulation cascade. [ ]

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Term info

Label

Abnormality of the intrinsic pathway

database cross reference

comment

The intrinsic pathway requires coagulation factors VIII, IX, X, XI, and XII, as well as the proteins prekallikrein (PK) and high-molecular-weight kininogen (HK or HMWK), in addition to calcium ions and phospholipids secreted from platelets.

created by

peter

creation date

2011-02-08T04:26:55Z

has obo namespace

human_phenotype

HP:0010989

Term relations

Equivalent to:

has_part some (
    process quality and
    inheres in some blood coagulation, intrinsic pathway and
    has modifier some abnormal)

Subclass of:

Abnormality of metabolism/homeostasis
Abnormality of the coagulation cascade