Terminology Service for NFDI4Health
Fetal ultrasound soft marker
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http://purl.obolibrary.org/obo/HP_0011425
An finding upon obstetric ultrasound examination performed at around 16 to 20 weeks of gestation that is abnormal but not clearly identifiable as a fetal anatomic malformation or growth restriction. Such findings are known as soft markers since they are associated with increased risk for fetal aneuploidy or other disorders. [ http://www.ncbi.nlm.nih.gov/pubmed/16100637 ]
Term info
Label
Fetal ultrasound soft marker
comment
The screening ultrasound at 16 to 20 weeks should evaluate 8 markers, 5 of which (thickened nuchal fold, echogenic bowel, mild ventriculomegaly, echogenic focus in the heart, and choroid plexus cyst) are associated with an increased risk of fetal aneuploidy, and in some cases with nonchromosomal problems, while 3 (single umbilical artery, enlarged cisterna magna, and pyelectasis) are only associated with an increased risk of nonchromosomal abnormalities when seen in isolation (PMID:16100637).
created by
peter
creation date
2012-03-17T04:26:01Z
has obo namespace
human_phenotype
id
HP:0011425