The presence of more than 5 juvenile polyps of the colon. The term juvenile polyps refer to a special histopathology and not the age of onset as the polyp might be diagnosed at all ages. The juvenile polyp has a spherical appearance and is microscopically characterized by overgrowth of an oedematous lamina propria with inflammatory cells and cystic glands. [ http://www.ncbi.nlm.nih.gov/pubmed/17768394 http://www.ncbi.nlm.nih.gov/pubmed/25022750 ]