Terminology Service for NFDI4Health
Abnormal protein N-linked glycosylation
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http://purl.obolibrary.org/obo/HP_0012347
An anomaly of protein N-linked glycosylation, i.e., an abnormality of the protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a nitrogen atom in an amino acid residue in a protein. [ http://www.ncbi.nlm.nih.gov/pubmed/22516080 ]
Term info
Label
Abnormal protein N-linked glycosylation
comment
Essentially, all proteins (except albumin) that travel through the ER-Golgi network undergo N-linked glycosylation. Glycans promote protein folding, stability, trafficking, localisation, and oligomerisation. They play vital parts in cell-cell interactions and intracellular signalling.
created by
peter
creation date
2013-09-15T09:29:59Z
has obo namespace
human_phenotype
id
HP:0012347
Term relations
Equivalent to:
- has_part some (
process quality and
inheres in some protein N-linked glycosylation and
has modifier some abnormal)